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College football Top 25 picks: Michigan meets Ohio State with much on line

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Illinois Michigan Football

Michigan quarterback J.J. McCarthy has thrown for 14 touchdowns with two interceptions.

It’s Thanksgiving week and you know what that means – rivalries. In the final regular-season weekend of college football, there are some huge games on the top-10 slate.

The stakes are as high as ever for "The Game."

When No. 3 Michigan (11-0) travels south to face No. 2 Ohio State (11-0) in Columbus on Saturday, a berth in the College Football Playoff will likely be on the line.

A year ago in Ann Arbor, the Wolverines dropped the Buckeyes and, in effect, punched their ticket to the Final Four. They destroyed Iowa in the Big Ten championship game, then were destroyed by Georgia in the CFP.

Ohio State has been bent on revenge ever since their Big House loss.

FrontPageBets digs in to this game and picks the entire Top 25 schedule.

(Odds courtesy of DraftKings and subject to change.)

Michigan outlook

The big question for the Wolverines is if leading rusher Blake Corum (1,457 yards, 18 touchdowns) will be able to play after suffering a knee injury is the first half last week against Illinois.

Quarterback J.J. McCarthy has thrown for 1,952 yards with 14 TDs and two picks. RB Donovan Edwards may need to fill in for Corum.

Receiver Ronnie Bell is the top pass catcher (641 yards, two scores).

The Wolverines rank No. 1 in total defense, yielding just 241.3 yards per game.  

They are 6-4-1 against the spread.

Ohio State outlook

The Buckeyes are coming off a closer-than-the-score-indicates 43-30 win at Maryland. QB C.J. Stroud (2,991 yards passing, 35 TDs, four interceptions) remains the Heisman Trophy favorite. Injuries have limited RB TreVeyon Henderson.

Wideout Marvin Harrison Jr.  (1,037 yards, 11 TDs) is the top big-play threat.

OSU's defense is rated ninth nationally (283.4 yards per game).

It is 5-5-1 ATS.

No. 3 Michigan vs. No. 2 Ohio State

When: Saturday, noon, FOX

  • Spread: Ohio State -7.5 (-110); Michigan +7.5 (-110)
  • Money line: Ohio State 295; Michigan +245
  • O/U: 56 (-110)
  • The pick: Ohio State, 28-21

Other Top 25 games

Mississippi State vs. No. 20 Ole Miss

  • When: Thursday, 7 p.m., ESPN
  • Spread: Ole Miss -2.5 (-105); Mississippi State +2.5 (-115)
  • Money line: Ole Miss -130; Mississippi State +110
  • O/U: 59 (-110)
  • The pick: Ole Miss, 31-24

No. 19 Tulane vs. No 24 Cincinnati

  • When: Friday, noon, ABC
  • Spread: Cincinnati -2 (-115); Tulane +2 (-105)
  • Money line: Cincinnati -130; Tulane +110
  • O/U: Over 46.5 (-115); Under 46.5 (-105) 
  • The pick: Cincinnati, 24-21

N.C. State vs. No. 17 North Carolina

  • When: Friday, 3:30 p.m., ABC
  • Spread: North Carolina -6.5 (-105); N.C. State +6.5 (-115)
  • Money line: North Carolina -240; N.C. State +200
  • O/U: 56 (-110)
  • The pick: North Carolina, 35-28

No. 18 UCLA vs. Cal

  • When: Friday, 4:30 p.m., FOX
  • Spread: UCLA -10 (-110); Cal +10 (-110)
  • Money line: UCLA -380; Cal +310
  • O/U: 60.5 (-110)
  • The pick: UCLA, 35-21

Florida vs. No. 16 Florida State

  • When: Friday, 7:30 p.m., ABC
  • Spread: Florida State -9.5 (-110); Florida +9.5 (-110)
  • Money line: Florida State -360; Florida +295
  • O/U: Over 58 (-105); Under 58 (-115)
  • The pick: Florida State, 31-24

Georgia Tech vs. No. 1 Georgia

  • When: Saturday, noon, ABC
  • Spread: Georgia -35.5 (-110); Georgia Tech +25.5 (-110)
  • Money line: Georgia -100000; Georgia Tech +8000
  • O/U: 49 (-110)
  • The pick: Georgia, 38-10

South Carolina  vs. No. 8 Clemson

  • When: Saturday, noon, ABC
  • Spread: Clemson -14.5 (-115); South Carolina +14.5 (-105)
  • Money line: Clemson -625; South Carolina +470
  • O/U: 52 (-110)
  • The pick: Clemson, 28-27

No. 25 Louisville vs. Kentucky 

  • When: Saturday, 3 p.m., SECN
  • Spread: Kentucky -2.5 (-120); Louisville +2.5 (+100)
  • Money line: Kentucky -155; Louisville +135
  • O/U: 43 (-110)
  • The pick: Kentucky, 28-24

Auburn vs. No. 7 Alabama

  • When: Saturday, 3:30 p.m., CBS
  • Spread: Alabama -22 (-110); Auburn +22 (-110)
  • Money line: Alabama -2400; Auburn +1200
  • O/U: 49.5 (-110)
  • The pick: Alabama, 28-17

No. 9 Oregon vs. No. 21 Oregon State

  • When: Saturday, 3:30 p.m., ABC
  • Spread: Oregon -3 (-110); Oregon State +3 (-110)
  • Money line: Oregon -155; Oregon State +135
  • O/U: 58 (-110)
  • The pick: Oregon, 38-31

Iowa State vs. No. 4 TCU

  • When: Saturday, 4 p.m., FOX
  • Spread: TCU -10 (-110); Iowa State +10 (-110)
  • Money line: TCU -365; Iowa State +300
  • O/U: 47.5 (-110)
  • The pick: TCU, 28-24

No. 14 Utah vs. Colorado

  • When: Saturday, 4 p.m., PAC12
  • Spread: Utah -30 (-110); Colorado +30 (-110)
  • Money line: Utah -10000; Colorado +3500
  • O/U: 52 (-110)
  • The pick: Utah, 38-10

Michigan State vs. No. 11 Penn State

  • When: Saturday, 4 p.m., FS1
  • Spread: Penn State -18 (-110); Michigan State +18 (-110)
  • Money line: Penn State -1150; Michigan State +750
  • O/U: 52.5 (-110)
  • The pick: Penn State, 31-21

No. 5 LSU vs. Texas A&M

  • When: Saturday, 7 p.m., ESPN
  • Spread: LSU -10 (-110); Texas A&M +10 (-110)
  • Money line: LSU -390; Texas A&M +320
  • O/U: Over 47.5 (-105); Under 47.5 (-115)
  • The pick: LSU, 31-17

No. 22 UCF vs. South Florida

  • When: Saturday, 7 p.m., ESPN2
  • Spread: UCF -19.5 (-110); South Florida +19.5 (-110)
  • Money line: UCF -1050; South Florida +700
  • O/U: 68.5 (-110)
  • The pick: UCF, 38-21

No. 10 Tennessee vs. Vanderbilt

  • When: Saturday, 7;30 p.m., SECN
  • Spread: Tennessee -14 (-110); Vanderbilt +14 (-110)
  • Money line: Tennessee -520; Vanderbilt +410
  • O/U: 64.5 (-110)
  • The pick: Tennessee, 42-24

No. 15 Notre Dame vs. No. 6 USC

  • When: Saturday, 7:30 p.m., ABC
  • Spread: USC -5.5 (-110); Notre Dame +5.5 (-110)
  • Money line: USC -210; Notre Dame +180
  • O/U: 64.5 (-110)
  • The pick: USC, 38-31

No. 12 Kansas State vs. Kansas

  • When: Saturday, 8 p.m., FOX
  • Spread: Kansas State -11.5 (-105); Kansas +11.5 (-105)
  • Money line: Kansas State -450; Kansas +360
  • O/U: 62.5 (-110)
  • The pick: Kansas State, 35-21

No. 13 Washington vs. Washington State

  • When: Saturday, 10:30 p.m., ESPN
  • Spread: Washington -2 (-110); Washington State +2 (-110)
  • Money line: Washington -130; Washington State +110
  • O/U: 60 (-110)
  • The pick: Washington, 35-34

Gambling problem? There is help. Call 1-800-522-4700 or visit the National Council on Problem Gambling for help.

Gerry Ahern is senior content editor for FrontPageBets. A 35-year veteran sports editor and digital media executive, he has led coverage of the biggest events in sports, from Super Bowls, to Final Fours, to Olympics, to the Masters.

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